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Sung-Han Lee Selected Research

Rimonabant

2/2010Synthesis and structure-activity relationship of 1,2,4-triazole-containing diarylpyrazolyl carboxamide as CB1 cannabinoid receptor-ligand.
12/2009Pentacycle derivatives as cannabinoid CB1 receptor ligands.
8/2009Substituted pyrimidines as cannabinoid CB1 receptor ligands.
8/2009Methylsulfonylpyrazolyl oxadiazoles and thiadiazoles as potent, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity.
4/2009Synthesis and structure-activity relationship of novel diarylpyrazole imide analogues as CB1 cannabinoid receptor ligands.
4/2009Oxadiazole-diarylpyrazole 4-carboxamides as cannabinoid CB1 receptor ligands.
1/2009Diarylimidazolyl oxadiazole and thiadiazole derivatives as cannabinoid CB1 receptor antagonists.
11/2008Biarylpyrazolyl oxadiazole as potent, selective, orally bioavailable cannabinoid-1 receptor antagonists for the treatment of obesity.
4/2008Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands.
4/2008Tetrazole-biarylpyrazole derivatives as cannabinoid CB1 receptor antagonists.

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Sung-Han Lee Research Topics

Disease

10Obesity
02/2010 - 04/2008
2Body Weight (Weight, Body)
03/2005 - 12/2003
1Atherosclerosis
03/2005
1Hyperthyroidism
03/2005

Drug/Important Bio-Agent (IBA)

10RimonabantIBA
02/2010 - 04/2008
5CB1 Cannabinoid Receptor (CB1 Receptor)IBA
02/2010 - 04/2008
4CannabinoidsIBA
12/2009 - 04/2008
2OxadiazolesIBA
08/2009 - 11/2008
2Polychlorinated Dibenzodioxins (TCDD)IBA
03/2005 - 12/2003
1Cannabinoid Receptors (Cannabinoid Receptor)IBA
08/2009
1ThiadiazolesIBA
08/2009
1Phosphoglycerate Mutase (Phosphoglyceromutase)IBA
03/2005
1Proteins (Proteins, Gene)FDA Link
03/2005
1apolipoprotein A-IV (apolipoprotein AIV)IBA
03/2005